MovDisordV3, Main, Exploration, bibRecord, 003A60

Prevalence and clinical features of Hedonistic homeostatic dysregulation in Parkinson's disease

Identifieur interne : 003A60 ( Main/Exploration ); précédent : 003A59; suivant : 003A61

Prevalence and clinical features of Hedonistic homeostatic dysregulation in Parkinson's disease

Auteurs : Francesca Romana Pezzella [Italie] ; Carlo Colosimo [Italie] ; Nicola Vanacore [Italie] ; Simone Di Rezze [Italie] ; Melania Chianese [Italie] ; Giovanni Fabbrini [Italie] ; Giuseppe Meco [Italie]

Source :

Movement disorders [ 0885-3185 ] ; 2005.

RBID : Pascal:05-0174090

Descripteurs français

Pascal (Inist)
- Système nerveux pathologie, Prévalence, Substance toxicomanogène, Parkinson maladie, Dopamine, Lévodopa, Addiction.

English descriptors

KwdEn :
- Addiction, Dopamine, Drug of abuse, Levodopa, Nervous system diseases, Parkinson disease, Prevalence.

Abstract

Hedonistic homeostatic dysregulation (HHD) is a neuropsychiatric disorder recently described in Parkinson's disease (PD), which is characterized by self-medication and addiction to dopaminergic drugs. To understand the prevalence of this disorder, we screened 202 PD patients attending our movement disorder unit for HHD. The clinical features of the patients identified as affected by this syndrome were then compared with those of control PD patients in an attempt to ascertain the possible risk factors for HHD. Results showed 7 subjects who fulfilled the HHD criteria. The analysis of a case-control study showed a significant correlation between HHD and a previous history of mood disorders, and the use of dopamine agonists, either in monotherapy or in combination. The prevalence of HHD in our study is similar to the one reported in the United Kingdom by the authors who first described this syndrome in PD. Of interest, our patients showed a somewhat different pattern of the disorder, suggesting that cultural and environmental factors may play a role in the phenomenology of HHD.

Affiliations:

Links toward previous steps (curation, corpus...)

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to stream Main, to step Merge: 005223
to stream Main, to step Curation: 003A60

Le document en format XML

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<front><div type="abstract" xml:lang="en">Hedonistic homeostatic dysregulation (HHD) is a neuropsychiatric disorder recently described in Parkinson's disease (PD), which is characterized by self-medication and addiction to dopaminergic drugs. To understand the prevalence of this disorder, we screened 202 PD patients attending our movement disorder unit for HHD. The clinical features of the patients identified as affected by this syndrome were then compared with those of control PD patients in an attempt to ascertain the possible risk factors for HHD. Results showed 7 subjects who fulfilled the HHD criteria. The analysis of a case-control study showed a significant correlation between HHD and a previous history of mood disorders, and the use of dopamine agonists, either in monotherapy or in combination. The prevalence of HHD in our study is similar to the one reported in the United Kingdom by the authors who first described this syndrome in PD. Of interest, our patients showed a somewhat different pattern of the disorder, suggesting that cultural and environmental factors may play a role in the phenomenology of HHD.</div>
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	Movement Disorders (revue)
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Movement Disorders (revue)

Prevalence and clinical features of Hedonistic homeostatic dysregulation in Parkinson's disease

Prevalence and clinical features of Hedonistic homeostatic dysregulation in Parkinson's disease

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri